Historians of science appear to agree on two things.There is a shortage of large-scale histories of science, and positivism is best avoided.In fact, we have many big-picture histories of science.The problem is not the lack of such histories but the lack of agreement between them.They differ with respect to chronology, geography, narrative structure
Renal angiomyolipoma (AML) rarely presents 1073spx with evidence of extension into the renal vein, inferior vena cava (IVC) or atrium.We report a case of a renal AML with a tumor thrombus to the IVC in a 32-year-old male.The patient subsequently underwent a right radical nephrectomy with IVC tumor thrombectomy.To our knowledge, there are four publi
Abstract Background Pathogenic gain of function variants in Valosin-containing protein (VCP) cause a unique disease il barone wine characterized by inclusion body myopathy with early-onset Paget disease of bone and frontotemporal dementia (also known as Multisystem proteinopathy (MSP)).Previous studies in drosophila models of VCP disease indicate t
The development of novel antimicrobial drugs is crucial due to the increasing problem of antibiotic resistance.A new series of 1,4-disubstituted-1,2,3-triazole derivatives containing a cytosine moiety (3a, 3b, 3c and 3d) were synthesized using 1,3-dipolar cycloaddition in a mixture of ethanol and water under Cu(I)-catalyzed with N-alkyl: 1-(prop-2-
Background: Tibial aplasia is of heterogeneous aetiology, the majority jmannino.com of reports are sporadic.We describe the reconstruction procedures in two subjects - a daughter and father manifested autosomal dominant (AD) inheritance of the bilateral tibial aplasia and split hand-foot syndrome.Materials and Methods: Reconstruction of these patie